and honors the wisdom of the body that we have acquired in living over the generations,
and asks: "What is the body trying to
questions has not been asked in western medicine because our framework, or
paradigm, is based on balancing the body's symptoms. When something is wet we
dry it; when something is hot we cool it. We inherited this paradigm
from the ancient Greeks along with many of our other social structures. The
Greeks began the concept of humoral medicine. When a person had a problem the
doctor decided which of his humors was acting up and used drugs and other means
to reduce that humor. When the patient was flushed and feverish he was considered
to be too sanguine and his arm was cut so that he could bleed.
The loss of blood led the body to try to save blood for the more important
internal organs by shutting down the circulation to the skin, so the flushed
appearance was successfully treated. And if they took enough blood the shock
eliminate the fever. It was very effective therapy for the symptoms, and, as
know today totally wrong.
section I look at two "problems" that we have dealt with by developing
medications that block our normal body processes. The question, as it was for
bleeding, remains: "Is this a
wise thing to do?" Joseph Chilton Pearce, in talking about
"The Roots of Intelligence" distinguishes between intelligence and
intellect. All living things have a degree of intelligence. Lewis Thomas, in
best selling book, Lives of a Cell, talks about the intelligence of
cells. Intelligence will not let us do something that will harm us. Intellect,
the other hand, is only constrained by, "Is it possible?" For the last
50 years our educational system has been geared at training the intellect in
order to have people capable of destroying the earth by nuclear war or more
slowly by environmental destruction. I believe that doing things that block our
normal body defenses is a good example of unrestrained intellect —of
intellect, in Pearce's words, "totally devoid of
we ask why certain symptoms develop, as biologists are
currently doing, we
learn that the symptoms can generally be classified as defenses, manipulations,
or side effects. Defenses are symptoms that actually help us deal with insults
such as fever, diarrhea, and a runny nose—we benefit.
Manipulations are symptoms that are stimulated by and benefit the invading
organism, such as the prostration associated with malaria, that makes the person
an easy target for hungry mosquitoes, or the enhanced diarrhea of cholera that
spreads more of the bacteria into the contaminated water supplies—the bacteria
benefit. Side effects, such as the dry eyes of a person with Bell's Palsy or
the hot flashes of menopause are just that—neither side benefits. Side effects
can be treated without problems,
manipulations need to be addressed by making the transmission more difficult—mosquito
nets and clean water supplies for the examples
given—but defenses need
to be honored and assisted.
with a backbone, and some without, can develop a fever. This is usually a
response to infection from bacteria or viruses. Most people realize that there
must be some advantage to a fever in such circumstances. And there is. The
immune system is responsible for keeping us healthy and it does this much more
effectively and efficiently when we have a fever. Rabbits die more
often from the infection when their fevers are blocked. Similar studies have not
been done on humans because the "harmful effects" of fevers have been
too widely accepted, but there is some indication that blocking fevers by using
drugs like ibuprofen actually increase our chances of becoming septic with serious
seizures are one of the more fearful consequences of a fever in a child. I
remember one of my mentors who was talking about febrile seizures. "If you
see a child with a febrile seizure," he said, "FOR HEAVENS SAKES, DON'T JUST DO
SOMETHING, STAND THERE." Febrile seizures do not harm the brain of the
child experiencing the seizure. The rub, of course, is knowing that the
seizure is caused by the fever. Since other causes of seizures can cause
problems in the brain we must treat unless we are certain. Several studies over
the past two hundred years have shown that people can tolerate high temperatures
without problems. Most of these studies have been done by warming the body from
outside in sweat lodges or military gear and the people were in good physical
condition. By far the most important thing these people did as their
temperatures went up was to drink.
is also the best thing to do when anyone has a fever from infection. Over
the years that I have worked in the emergency room I have seldom seen anything
make people feel better when they are ill, from almost any problem, than an IV.
So drinking is the best thing to do for a fever. And make the person as comfortable
as possible. If that means
they bundle up in bed with the electric blanket on high, that is probably OK.
they ache all over acetaminophen can help, but it will also lower the
temperature. Again, the best thing to do is stay really well hydrated so that
your body can wash out their infection more effectively.
For me this means ORAL REHYDRATION, which brings us to our next topic.
something irritates the bowel the body responds by trying to wash it out. Again,
for the body, the solution to pollution is dilution. This problem, as much of
a nuisance as it is, is a normal defensive process. When it is caused by
and we take medication to stop the diarrhea we do promote more problems - more
of the bacteria set up housekeeping in our gut. A large part of the people
who suffer from irritable bowel disease have had an episode of infectious
diarrhea before the onset of their irritable bowel. I wonder how many of them
used pharmaceutical agents that slow gut movement during this illness. My own
personal experience using oral rehydration is that the diarrhea stops faster
people usually feel better faster than with any other way of dealing with
One of the real success stories of the last century is one that we don't often
hear about. Public health efforts in this country have largely prevented the
cholera epidemics that we had in the 19th century. Less developed countries
continued to have these epidemics until the latter part of the 20th century. A
single epidemic would often cost hundreds and sometimes thousands of lives.
Oral rehydration was developed in the 1960's and 70's as an adjunctive treatment
for cholera. In fact it is the only treatment necessary. People with cholera
don't die from the bacteria or from the toxin it releases; they die from
dehydration. The immune system knows that the toxin will kill us if it gets
inside the tissues and organs of the body so it opens every conceivable tap to
wash it out. This takes water from other critical places in the body
damaging the function of the heart, brain, and kidneys that leads to the death
of the patient. We routinely give antibiotics to people with cholera because
it cuts the time they shed the cholera bacteria from about four days to about
two days. But the only treatment they need is fluids. With epidemics
involving thousands of people there were not sufficient resources either in IV
solutions or in people trained to put them in. They needed a different way to
help the body.
rehydration utilizes the sodium glucose transport system that is in the
cells of the stomach and intestine, to get adequate fluids into the body.
used to think that this system got water into the body by osmosis – the
sodium and sugar got pumped into the body and the water followed.
has shown that this system is actually a
water pump – one molecule of glucose, two of sodium, and 210 of water are
actively pumped from the stomach into the blood stream, even against an
osmotic gradient. That amount of fluid is every bit as good as an IV, and that
amount of fluid is what was needed to treat the thousands of people dying with
the rise of resistant bacteria, complications from anti-motility agents,
and more recently from the antibiotics themselves
which often compound problems,
more physicians are promoting the use of oral rehydration as the first line
treatment for diarrheal illness. In my practice it has been one of the most
useful and effective ways of treating gastrointestinal disorders as well as
keeping people well hydrated in the presence of any kind of illness. The British Medical Society said
that oral rehydration may be one of the most significant medical advances of
In this country we have no category of "foods with drug effects" so
anything, including a solution of sugar, salt and water, becomes a
"drug" if it is intended to prevent or treat an illness. That
is why most of us have never even heard of this sensible treatment, it is "grossly underused", and why "Pedialyte",
the most common oral rehydration solution in this country, remains a food, without
claims or treatment indications. There is now available a commercial product
that matches the World Health Organizations recipe for oral rehydration available
Brothers Packaging in Kansas City, Mo. The packet price is around $0.50 which
is the same as the the WHO packets available throughout the world. They sell
by the carton so this is an item that your health food store or locally owed
pharmacy is going to have to stock. Janias Brothers can be reached at (816)
421-2880. If you need help convincing your local supplier feel free to copy
these pages and take it to them. Oral rehydration should be available to and
the shelf of every
person in the country.
The following information has been among the most useful in helping people
maintain good health in my practice. If you can't get someone to stock it
for you this is an approximation that has worked well for me.
Who should use it?
needs to replace fluids or who needs a little extra fluid because of illness,
such as the fever discussed above. Definitely people with gastrointestinal
losses should use this. That is what it is designed for. Whenever someone is ill
an IV will usually make them feel better. This is an IV you can drink. Pregnant
women with nausea and vomiting can usually tolerate this and it prevents
the dehydration that is usually treated with an IV. Extra fluid is always
helpful when one is dealing with infection –
it helps the washing. I have even used this successfully with diabetics who are
vomiting, but vomiting diabetics can have serious problems and should be in a hospital.
anyone not use it?
heart disease can get too much fluid and develop what is called congestive heart
failure. Oral rehydration is not a good idea for them. If a person has an ulcer
that is perforating the wall of their stomach they will have a whole lot of pain
and their stomach will be rigid. Putting anything in a stomach with holes is not
How is it made?
teaspoon salt substitute (read the little print on the package, this should
teaspoon baking soda, and
3 tablespoons white corn
syrup (eg. Karo).
other than babies this may be flavored with juice concentrate or unsweetened
powdered drink mix such as Kool-Aid.
warning: measure the baking soda and salt substitute carefully to prevent
How should it be used?
chug-a-lug it, but this is not recommended. Best is to think of it as an IV and
drink small amounts regularly. The journal Pediatrics in
an article entitled "Vomiting and Diarrhea" recommends the following
steps for infants
that can easily be adapted upward for older people:
Step 1. Wait one hour after the last
episode of vomiting.
Step 2. Give
1/2 oz. (15cc) to an infant or 1 oz. (30cc) to a child over one year old every
20 minutes for one to two hours. If an infant is being breast fed only two
feedings of oral rehydration are all that is usually necessary.
Step 3. If
vomiting does not recur, increase the amount gradually. The goal is to replace
the fluids lost within six hours. If vomiting does return go back to step 1.
If you have gone through this cycle
three times go to the doctor.
Step 4. Advance the diet and resume
normal diet in 12 to 24 hours.
to your body, don't force anything on it that doesn't feel right. When you are
adequately hydrated your body will know.
Why use this?
In this day
when we can stop diarrhea with a pill and calm and upset stomach with a shot why
should one go through the turmoil? The best answer is to trust your immune
system and try to support it in what it feels is best for your body. Some people
whose diarrhea is caused by bacteria become carriers of those harmful bacteria
when their diarrhea is stopped with medication. Some children have died of
infection when they were given medicine that stopped their diarrhea. Trust your
Continue reading about How
to Help Wash the Nose
more about Common Sense Medicine
and how it can affect our health care system. [This is a different web page.]
- The risk of the hemolytic-uremic syndrome after
antibiotic treatment of Escherichia coli O157:H7 infections.
Wong CS, Jelacic S, Habeeb RL, Watkins SL, Tarr PI
Children's Hospital and Regional Medical Center and the University of
Washington School of Medicine, Seattle 98105, USA.
BACKGROUND: Children with gastrointestinal infections caused by Escherichia
coli O157:H7 are at risk for the hemolytic-uremic syndrome. Whether
antibiotics alter this risk is unknown. METHODS: We conducted a prospective
cohort study of 71 children younger than 10 years of age who had diarrhea
caused by E. coli O157:H7 to assess whether antibiotic treatment in these
children affects the risk of the hemolytic-uremic syndrome and to assess the
influence of confounding factors on this outcome. Estimates of relative
risks were adjusted for possible confounding effects with the use of
logistic-regression analysis. RESULTS: Among the 71 children, 9 (13 percent)
received antibiotics and the hemolytic-uremic syndrome developed in 10 (14
percent). Five of these 10 children had received antibiotics. Factors
significantly associated with the hemolytic-uremic syndrome were a higher
initial white-cell count (relative risk, 1.3; 95 percent confidence
interval, 1.1 to 1.5), evaluation with stool culture soon after the onset of
illness (relative risk, 0.3; 95 percent confidence interval, 0.2 to 0.8),
and treatment with antibiotics (relative risk, 14.3; 95 percent confidence
interval, 2.9 to 70.7). The clinical and laboratory characteristics of the 9
children who received antibiotics and the 62 who did not receive antibiotics
were similar. In a multivariate analysis that was adjusted for the initial
white-cell count and the day of illness on which stool was obtained for
culture, antibiotic administration remained a risk factor for the
development of the hemolytic uremic syndrome (relative risk, 17.3; 95
percent confidence interval, 2.2 to 137). CONCLUSIONS: Antibiotic treatment
of children with E. coli O157:H7 infection increases the risk of the
- N Engl J Med. 2000 Jun 29;342(26):1990-1
The human Na+-glucose cotransporter is a molecular water
Meinild A, Klaerke DA, Loo DD, Wright EM, Zeuthen T
The Panum Institute, University of Copenhagen, Department of Medical
Physiology, Blegdamsvej 3, DK-2200N Copenhagen, Denmark.
1. The human Na+-glucose cotransporter (hSGLT1) was expressed in Xenopus
laevis oocytes. The transport activity, given by the Na+ current, was
monitored as a clamp current and the concomitant flux of water followed
optically as the change in oocyte volume. 2. When glucose was added to the
bathing solution there was an abrupt increase in clamp current and an
immediate swelling of the oocyte. The transmembrane transport of two Na+
ions and one sugar molecule was coupled, within the protein itself, to the
influx of 210 water molecules. 3. This stoichiometry was constant and
independent of the external parameters: Na+ concentrations, sugar
concentrations, transmembrane voltages, temperature and osmotic gradients.
4. The cotransport of water occurred in the presence of adverse osmotic
gradients. In accordance with the Gibbs equation, energy was transferred
within the protein from the downhill fluxes of Na+ and sugar to the uphill
transport of water, indicative of secondary active transport of water. 5.
Unstirred layer effects were ruled out on the basis of experiments on
oocytes treated with gramicidin or other ionophores. Na+ currents maintained
by ionophores did not lead to any initial water movements. 6. The finding of
a molecular water pump allows for new models of cellular water transport
which include coupling between ion and water fluxes at the protein level;
the hSGLT1 could account for almost half the daily reuptake of water from
the small intestine.
|Lancet 1978 Aug 5;2(8084):300-1
Water with sugar and salt.
Oral rehydration therapy for diarrhea: an example of
reverse transfer of technology.
Santosham M, Keenan EM, Tulloch J, Broun D, Glass R.
Johns Hopkins University, Center for American Indian and Alaskan Native
Health, Baltimore, MD 21205, USA.
On November 13 and 14, 1996, a scientific symposium on oral rehydration
therapy (ORT) was held at the Johns Hopkins University School of Hygiene
and Public Health in Baltimore, MD. The purpose of the meeting was to
current treatment practices for the treatment of this disease in the
United States. The group noted that diarrhea resulted in 300 to 400 deaths
among children, approximately 200 000 hospitalizations, 1.5 million
outpatient visits, and costs >$1 billion in direct medical costs.
ORT is well established therapy for the treatment and prevention of dehydration
to diarrhea. The principles of ORT treatment include early adequate
rehydration therapy using an appropriate oral rehydration solution (ORS),
replacement of ongoing fluid losses from vomiting and diarrhea with ORS,
and frequent feeding of appropriate foods as soon as dehydration is corrected.
The effective use of ORT has saved millions of lives around the world.
However, in the United States, ORT is grossly underused. Contrary to
recommendations of the American Academy of Pediatrics (AAP) and the Centers
for Disease Control and Prevention (CDC), health care providers overuse
intravenous hydration, prolong rehydration, delay reintroduction of feeding,
and inappropriately withhold ORT, especially with children who are vomiting.
The expert panel noted that the majority of deaths, hospitalization,
and visits to emergency departments could be prevented by the appropriate
ORT. They generated guidelines for the treatment and prevention of
dehydration secondary to diarrhea. These measures, together with training
providers, could substantially reduce diarrhea mortality and decrease
hospitalizations of children by 100 000 per year in the next 5 years.
Could nonsteroidal antiinflammatory drugs (NSAIDs) enhance
the progression of bacterial infections to toxic shock syndrome?
Infectious Diseases, Veterans Affairs Medical Center, Boise, Idaho 83702, USA.
Anecdotal reports suggest an association between the use of nonsteroidal
antiinflammatory drugs (NSAIDs) and the progression of invasive group A
streptococcal infections to shock and multiorgan failure. There is a biochemical
rationale that could support this theory. Though NSAIDs are frequently used to
relieve pain or reduce fever, they also attenuate granulocyte functions such as
chemotaxis, phagocytosis, and bacterial killing. In addition, findings in recent
studies involving human volunteers injected with endotoxin suggest that
pretreatment with NSAIDs enhances production of tumor necrosis factor, which
leads to higher blood levels of this cytokine, probably by preventing feedback
inhibition by prostaglandin E2. Thus, NSAIDs may contribute to the sudden onset
of shock, organ failure, and aggressive infection by inhibiting neutrophil
function, augmenting cytokine production, and attenuating the cardinal
manifestations of inflammation.
Vomiting and diarrhea.
Vomiting and diarrhea are frequently encountered in pediatric patients.
Dehydration, a serious consequence of both vomiting and diarrhea, results in
the deaths of more than 700 children annually in the United States. With
appropriate parent education, both morbidity and mortality can be reduced,
and much of the anxiety about these problems can be alleviated. Parents must
be educated to recognize the associated signs and symptoms that indicate
serious disease and warrant notifying the physician. Fluid therapy should be
individualized, and parents should be informed of the appropriate steps to
take. Parents must make quantitative observations and keep records not only
to enable the physician to assess adequate fluid balance but also to be able
to demonstrate to themselves the effectiveness of the treatment. It is just
as important for the physician to reassure parents, who will have concerns
about long-term nutritional or growth consequences.
The spray described in these pages
is not a drug. This means that the people manufacturing this spray
cannot advertise what the spray does to prevent disease and illness.
The spray only helps to clean your nose. The benefits come from
a clean nose. The only way people will learn about this practical
and sensible way to help the immune system wash pollutants from
the back of the nose is by interested people, like you, sharing
If you have family or friends with any of these problems, they
may benefit greatly from your sharing this information with them.
Links in the other sections, referring to a person or study, will
take you to a Medline summary, from the National Library of Medicine,
of the article in question.
This spray is protected by United States and international patents.
While careful reading of these pages will tell you how to mix this
spray yourself we request that you do not sell such spray on the
open market. Such sales would be prohibited by the above mentioned
Disclaimer: All material provided in this web site is provided
for educational purposes in the hope of improving our general health.
Access of this web site does not create a doctor-patient relationship
nor should the information contained on this web site be considered
specific medical advice with respect to a specific patient and/or
a specific condition. Copy sections of this page and discuss them
with your physician to see if they apply to your own symptoms or
Dr. Jones specifically disclaims any liability, loss or risk, personal
or otherwise, that is or may be incurred as a consequence, directly
or indirectly, of use or application of any of the information
provided on this web site.
A. H. 'Lon' Jones D.O.
812 West 8th St. Suite 2A
Plainview, Texas 79072
Phone (806) 291-0700
Fax (806) 293-8229